Regulators of regulatory pathway: Pyrimidine metabolism

All displayed regulators are experimentally validated.


Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0106 experimental vp2049 (Thymidylate kinase, Tmk) T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0210 experimental ETAE_2082 (pyrF) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2196136..2196858 (-) 502611934 ETAE_0886 (esrB) promoter (↑)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0106 experimental vp2049 (Thymidylate kinase, Tmk) T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0210 experimental ETAE_2082 (pyrF) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2196136..2196858 (-) 502611934 ETAE_0886 (esrB) promoter (↑)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)